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An unbiased genome-wide shRNA screen was performed in A375 human melanoma cells to globally evaluate genetic vulnerabilities to G4-ligands and to identify genes and pathways involved with G4-structures .For this, the pyridine-2,6-bis-quinolino-dicarboxamide derivative, PDS Rodriguez et al., 2012, and bisquinolinium compound, PhenDC3 De Cian et al., 2007b were chosen .
MINING Heavy Industries Co., Ltd. China(Mainland)
With more than 40 years manufacture experience, Fote Machinery has been a reliable solution for quarrying, building, road infrastructure and recycling projects around the world.
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